Compounded · Vitality

NAD+ Nasal Spray

The same coenzyme. Daily. Needle-free.

NAD+ powers the cellular machinery that turns food into energy and keeps DNA repair humming — and it falls measurably through midlife. The intranasal route delivers it through the rich vascular bed in your nose, no injection required. Daily dosing keeps levels steady rather than relying on a weekly peak.

Daily intranasal dose — takes seconds, no needles
Steady-state delivery rather than weekly peak-and-trough
Compounded by a state-licensed U.S. pharmacy
Includes clinician oversight, dose adjustment, and side-effect support
Direct-to-door · cancel anytime on monthly · save more on 6 or 12-month plans

Start your assessment

Why the spray

For women who'd rather not pick up a needle.

Woman in midlife considering her care options

The injection is the more direct route — we don't pretend otherwise. But injections aren't for everyone, and a needle isn't the right reason to put off a protocol that might genuinely help. The nasal route delivers NAD+ across the nasal mucosa straight into systemic circulation, bypassing the gut and liver where oral precursors lose most of their dose.

Daily dosing is the trade-off. Instead of a single weekly peak, you maintain a steadier baseline. Many women prefer this rhythm — it folds into a morning routine the same way a vitamin or skincare step does, and there's nothing to schedule.

For women who want to start gently, who travel often, or who simply don't want injections in the picture, the spray is a reasonable place to begin. If you don't notice a meaningful shift after 6–8 weeks, your clinician can talk through whether the injection might be the better fit.

Dosing & what to expect

A daily rhythm. Built into your morning.

Week 1 · Find your tolerance

Start with one spray per nostril, once daily, in the morning. Mild nasal tingling or a brief metallic taste is common in the first few days and almost always settles. If you feel jittery, your clinician may adjust the timing.

Weeks 2–4 · Build the steady state

Most women move to two sprays per nostril, once or twice daily, depending on the protocol. Effects build gradually — you're more likely to notice a steadier afternoon than a single dramatic shift.

Ongoing · Care, not just refills

Your plan includes clinician check-ins, dose adjustment, side-effect support, and the option to switch to the injection or layer in another protocol if your picture changes.

Side effects & safety

What to know before you start.

Woman reviewing health information at home

Most common: brief nasal tingling or burning, a metallic taste at the back of the throat, occasional mild headache, mild post-nasal drip. These are typically dose-related and resolve as your tissue acclimates.

Less common but worth flagging: jitteriness, palpitations, or sleep disruption if dosed too late in the day. Skip a dose if you have an active sinus infection or significant nasal congestion — absorption will be unreliable.

Not appropriate if: you have an active malignancy under treatment, are pregnant or breastfeeding, have an unstable cardiovascular condition, or have chronic nasal pathology that affects mucosal absorption. Tell your clinician about all medications and supplements.

Compounded medication notice

Compounded NAD+ nasal spray is dispensed by state-licensed U.S. pharmacies in FDA-regulated facilities under the patient-specific 503A exception. It is not FDA-approved as a finished product. NAD+ for vitality use is considered an emerging therapeutic area; your clinician will determine whether it is appropriate for your specific health profile.

Questions

Answers to
common questions.

Is the spray as effective as the injection?

Different absorption profile, but a real option — and the one you'll actually use is the one that works.

The injection has higher peak bioavailability per dose. The spray delivers smaller amounts more frequently, producing a steadier baseline rather than a weekly peak. For some women that steadiness is what they actually feel; for others, the weekly peak is more noticeable. The protocol you'll keep up with consistently is the one that works — that judgment is part of what your clinician helps with.

How is this different from oral NMN or NR supplements?

Intranasal absorption skips most of the gut and liver losses.

NMN and NR are precursors that have to be converted to NAD+, and a meaningful share of an oral dose is degraded before it reaches systemic circulation. Intranasal delivery of NAD+ itself bypasses most of that loss. It's a more reliable way to know you're actually receiving the dose your clinician chose.

When am I charged?

Not until a clinician confirms your eligibility.

You're not charged when you submit. Your card is saved. A licensed clinician reviews your assessment, typically within 24 hours. If approved, you'll be notified by email before the first charge. If not approved, you're not charged.

Can I cancel?

Yes — with full transparency on what you've committed to.

Yes. The 1-month plan can be cancelled anytime. The 6 and 12-month plans are committed terms billed monthly — cancel future renewals after the term ends.